Product description
Upstream Master Gene Inhibition to Block Melanin Synthesis at the Source (Unique Core Pathway) By mimicking the skin's endogenous TGF-β signaling, this peptide downregulates the melanocyte master transcription factor MITF, simultaneously suppressing four key melanogenesis-related genes—TYR, TRP-1, and TRP-2—thereby reducing melanin precursor production at the genetic level. Unlike conventional whitening ingredients that only inhibit tyrosinase, it competitively binds to the MC1R receptor, blocking α-MSH-mediated melanogenic signaling to provide a dual-action depigmenting mechanism. Clinical studies demonstrated a 38% reduction in pigmentation intensity after 12 weeks. In Asian subjects, 87% achieved a more even skin tone and 91% experienced visibly brighter skin after 56 days. The depigmenting efficacy was comparable to, or even superior to, 4% hydroquinone, without the risk of hydroquinone-induced exogenous ochronosis.
Reduces Multiple Types of Hyperpigmentation and Restores Radiant Skin Tone Continuously suppresses excessive melanin deposition triggered by UV exposure and inflammatory stimuli, helping improve melasma, sun spots, age spots, post-inflammatory hyperpigmentation (PIH), and post-acne erythema. Increases epidermal L* value to enhance skin translucency while reducing dullness, sallowness, and glycation- or photoaging-induced discoloration. Long-term use promotes a brighter, clearer, and more even complexion with minimal risk of rebound pigmentation or uneven lightening.
Broad-Spectrum Antioxidant and Anti-Inflammatory Brightening for Sensitive Skin Effectively scavenges ROS generated by UV radiation and blue light, reducing oxidative stress-induced melanogenesis. Downregulates inflammatory cytokines including IL-6 and TNF-α, helping soothe redness, irritation, and discomfort associated with chemical exfoliation, minimally invasive procedures, or compromised skin barriers. Simultaneously supports barrier repair during brightening treatment, making it suitable for long-term morning and evening use, even on sensitive skin, thin skin, and post-aesthetic treatment skin. Patch testing demonstrated very low irritation potential.
Additional Dermal Anti-Aging and Wrinkle Reduction Benefits Gently activates fibroblasts to moderately increase the expression of Type I collagen and fibronectin, while mildly inhibiting matrix metalloproteinases (MMPs) responsible for extracellular matrix degradation. Helps improve dehydration lines, superficial fine wrinkles, and photoaging-induced skin laxity, delivering dual benefits of skin brightening and early anti-aging, making it ideal for multifunctional anti-aging eye creams and advanced serum formulations.
Its low-molecular-weight structure enables gentle skin penetration and excellent compatibility with all skin types, including the delicate eye area. It causes no muscle paralysis, no dependency, and no rebound pigmentation after discontinuation. Manufactured in a standardized GMP-certified clean production facility with comprehensive quality control documentation, it is suitable for professional depigmenting, sensitive-skin brightening, and anti-photoaging skincare formulations.
For use as a cosmetic ingredient only. Not for oral consumption or subcutaneous injection.