Product description
This advanced cosmetic peptide ingredient targets elastin and tropoelastin biosynthesis to improve skin firmness and combat visible signs of skin laxity. By activating fibroblast signaling pathways within the dermis, it significantly upregulates the production of elastin, tropoelastin, and fibrillin, while simultaneously inhibiting elastase-mediated degradation. In vitro studies have demonstrated a 94% increase in elastin deposition, helping restore the skin's elastic fiber network. Clinical evaluation over eight weeks showed a 28% improvement in skin firmness and a 34% increase in dermal density, visibly improving sagging skin, enlarged pores, loss of elasticity, and fine lines around the eyes while rebuilding the skin's natural elastic support matrix.
The ingredient also provides exceptional soothing and barrier-repair benefits by regulating the POMC signaling pathway and reducing the release of calcitonin gene-related peptide (CGRP), thereby lowering cutaneous neurogenic sensitivity. It suppresses inflammatory mediators including IL-6 and TNF-α to relieve redness, burning, and stinging caused by seasonal changes, exfoliating acids, UV exposure, and other external stressors. Simultaneously, it promotes the expression of filaggrin and aquaporin-3 (AQP3), reinforcing the epidermal barrier, enhancing long-lasting hydration, and supporting sensitive and post-procedure skin.
With broad-spectrum antioxidant activity, the peptide scavenges reactive oxygen species (ROS) generated by UV radiation and blue light while downregulating cellular senescence markers, including β-galactosidase, and regulating p16, p21, and p53 signaling pathways. These effects help delay fibroblast aging, reduce oxidative degradation of collagen and elastin fibers, and improve roughness, dullness, and loss of skin fullness associated with photoaging. When combined with sunscreen formulations, it provides enhanced long-term protection against premature skin aging.
The ingredient further supports dermal regeneration by activating the TGF-β pathway, promoting the synthesis of type I and type III collagen together with fibronectin while suppressing matrix metalloproteinase-1 (MMP-1). This dual mechanism simultaneously increases dermal structural proteins and reduces extracellular matrix degradation, visibly improving static wrinkles, nasolabial folds, and overall skin density. It is ideally suited for comprehensive anti-aging formulations targeting both facial and periocular skin.
In addition to facial skincare, the peptide also benefits scalp care by improving dermal elasticity and strengthening follicular support. It helps reduce scalp laxity, reinforce weakened hair roots, and, when combined with hair-growth peptides, may support prolonged hair follicle growth cycles and reduce hair shedding.
Its low-molecular-weight structure offers excellent skin penetration and compatibility, making it suitable for long-term morning and evening use on all skin types, including the delicate eye area. It causes no muscle paralysis, dependency, or rebound effects after discontinuation. Manufactured under standardized GMP-compliant cleanroom conditions, the ingredient is supplied with complete quality control and regulatory documentation. It is suitable for cosmetic formulations targeting firming, anti-aging, soothing repair, post-procedure recovery, and scalp care.
This product is intended solely as a cosmetic ingredient for external use. It is not intended for oral administration or subcutaneous injection.